Searchable abstracts of presentations at key conferences in endocrinology

ea0070ep82 | Bone and Calcium | ECE2020

NCKX3 deficiency impairs to motor function and social behavior in mice

Yi Donglin , Nam Tran Dinh , Mi Park Seon , Thuy Vo Thi Bich , Jung Eui-Man , Jeung Eui-Bae

Ca2+ homeostasis has been reported to play important roles in various cell systems. In central nerves system, the dysregulation of Ca2+ homeostasis can induce the excitotoxic and neurodegeneration. NCKX3 (Sodium/potassium/calcium exchanger 3), a novel member of the family of K+-dependent Na+/Ca2+ exchangers, is an important component of intracellular Ca2+ homeostasis. In addition, NCKX3 highly expressed in tha...